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Senior Machine Learning Scientist | Natera | Remote (United States)

February 19, 2026

POSITION SUMMARY: Natera is seeking a highly skilled Machine Learning Scientist to contribute to cutting-edge research and development within our Artificial Intelligence and Machine Learning team, focused on molecular therapeutics and biomarker discovery. The successful candidate will play a key role in implementing and expanding state-of-the-art deep learning models and foundation models within the biomedicine space, leveraging extensive hands-on experience and a proven track record. You will also work closely with researchers and medical professionals to interpret model results and revolutionize medical diagnostics and treatments. RESPONSIBILITIES: <ul> <li>Design, implement, and evaluate deep learning models, such as deep sequence and biomedical foundation models, with scientific rigor for applications in therapeutics, prognostics, and diagnostics.</li> <li>Independently explore and stay current with the latest advancements in AI/ML and biomedical literature, applying cutting-edge AI/ML approaches to solve complex problems in molecular diagnostics and therapeutics.</li> <li>Interpret machine learning models by explainable AI methods (e.g. GradCAM, Shap) on diverse data modalities, such as genomics, transcriptomics and imaging, generating insights to enhance model transparency and trust.</li> <li>Document code and model by maintaining well-structured, readable, and reproducible workflows. Use version control systems (e.g. Git) and reproducible demos (e.g. Jupyter notebooks) to ensure consistency across projects.</li> <li>Communicate scientific results effectively through internal meetings, external conferences, and peer-reviewed publications, translating complex technical concepts for both technical and non-technical audiences.</li> <li>Collaborate with domain experts such as medical professionals, bioinformaticians, and statisticians to guide and refine R&D efforts in AI-driven medical diagnostics and therapeutics.</li> </ul> QUALIFICATIONS: <ul> <li> PhD in Computer Science, Statistics, Bioinformatics, or a related quantitative field </li> </ul> KNOWLEDGE, SKILLS, AND ABILITIES: <ul> <li>Proven experience with deep sequence models, biomolecular foundation models, graph neural networks, modality fusion, representation learning, generative models, and self-supervised learning techniques; and a demonstrated track record of machine learning applications to genomics, proteomics, and/or multi-omics big data.</li> <li>Highly proficient in PyTorch, lightning, tensorboard, captum, scikit-learn, transformers, and Huggingface APIs.</li> <li>Experience with SQL databases (snowflake and mysql-server).</li> <li>Experience in Git, jupyter notebook, and advanced visualizations (seaborn, plotly)</li> <li>Experience with AWS, single and multiple GPU-accelerated environments</li> <li>Ability to clearly summarize and communicate results in oral and written form.</li> <li>High scientific rigor and eagerness to teach and learn about new machine learning methods and biology.</li> <li>Experience with oncology or immunology is a plus</li> <li>Experience with medical imaging and joint modeling of cancer genomics and imaging is a plus</li> </ul> <div class='"content-conclusion"'> OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits – Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit <a href="//www.natera.com/%22" rel="nofollow">www.natera.com</a>. Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: <a href="//www.natera.com/notice-of-data-collection-california-residents%22" rel="nofollow noopener" target='"_blank"'>https://www.natera.com/notice-of-data-collection-california-residents/</a> Please be advised that Natera will reach out to candidates with a @<a href="//natera.com/%22" rel="nofollow noopener" target='"_blank"'>natera.com</a> email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: – <a href="//www.bbb.org/article/tips/12261-bbb-tip-employment-scams%22" rel="nofollow noopener" target='"_blank"'>BBB announcement on job scams</a> – <a href="//www.fbi.gov/investigate/cyber%22" rel="nofollow noopener" target='"_blank"'>FBI Cyber Crime resource page</a> </div> <img decoding="async" src="https://remotive.com/job/track/1940848/blank.gif?source=public_api" alt="" />

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...

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